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020 _a9781420015737 (ebook : PDF)
040 _aFlBoTFG
_cFlBoTFG
090 _aRM301.25
_b.I48 2006
092 _a615.19
_bI351
245 0 0 _aIn silico technologies in drug target identification and validation
_h[electronic resource] /
_cedited by Darryl Le�on, Scott Markel
260 _aBoca Raton :
_bCRC/Taylor & Francis,
_cc2006
300 _a490 p. :
_bill. (some col.)
490 _aDrug discovery series ;
_v
504 _aIncludes bibliographical references and index
505 _aPattern matching / Scott Markel and Vinodh N. Rajapakse -- Tools for computational protein annotation and function assignment / Jaume M. Canaves -- The impact of genetic variation on drug discovery and development / Michael R. Barnes -- Mining of gene expression data / Aedin Culhane and Alvis Brazma -- Text mining / Bruce Gomes, William Hayes, and Raf Podowski -- Pathways and networks / Eric Minch and Ivayla Vatcheva -- Molecular interactions: learning from protein complexes / Ana Rojas, David de Juan, and Alfonso Valencia -- In silico siRNA design / Darryl Le�on -- Predicting protein subcellular localization using intelligent systems / Rajesh Nair and Burkhard Rost -- Three-dimensional structures in target discovery and validation / Se�an I. O'Donoghue, Robert B. Russell, and Andrea Schafferhans -- Comparative genomics / Viviane Siino, Bruce Pascal, and Christopher Sears -- Pharmacogenomics / Bahram Ghaffarzadeh Kermani -- Target identification and validation using human simulation models / Seth Michelson, Didier Scherrer, and Alex L. Bangs -- Using protein targets for in silico structure-based drug discovery / Tad Hurst -- Database management / Arek Kasprzyk and Damian Smedley -- BioIT hardware configuration / Philip Miller -- BioIT architecture: software architecture for bioinformatics research / Michael Dickson -- Workflows and data pipelines / Michael Peeler -- Ontologies / Robin A. McEntire and Robert Ste
530 _aAlso available in print edition.
_bCRC Press (http://www.crcpress
538 _aMode of access: World Wide
650 _aDrug develop
650 _aDrug development
_xComputer simula
655 _aElectronic books.
700 _aLe�on,
700 _aMarkel,
776 _z978157
856 _uhttp://marc.crcnetbase.com/isbn/9781420015737
_qapplication/PDF
_zDistributed by publisher. Purchase or institutional license may be required for
999 _c15189
_d15189