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007 cr |||||||||||
008 150608s2015 enk ob 001 0 eng
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019 _a930802262
020 _a9781118734490 (epub)
020 _a1118734491 (epub)
020 _a9781118734483 (pdf)
020 _a1118734483 (pdf)
020 _z9781118734513 (cloth)
020 _a9781118734506
020 _a1118734505
020 _a1118734513 (cloth)
020 _a9781118734513 (cloth)
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035 _a(OCoLC)910914875
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049 _aMAIN
245 0 0 _aNovel delivery systems for transdermal and intradermal drug delivery /
_cRyan F. Donnelly, Thakur Raghu Raj Singh.
264 1 _aChichester, West Sussex :
_bJohn Wiley and Sons, Ltd,
_c2015.
300 _a1 online resource.
336 _atext
_2rdacontent
337 _acomputer
_2rdamedia
338 _aonline resource
_2rdacarrier
490 1 _aAdvances in pharmaceutical technology
504 _aIncludes bibliographical references and index.
505 0 _aIntroduction / Gary P.J. Moss -- Application of spectroscopic techniques to interrogate skin / Jonathan Hadgraft, Rita Mateus and Majella E. Lane -- Analysis of the native structure of the skin barrier by cryo-tem combined with em-simulation / Lars Norlen -- Intradermal vaccination / Marija Zaric and Adrien Kissenpfennig -- Film forming and heated systems / William J. McAuley -- Nanotechnology-based applications for transdermal delivery of therapeutics / Venkata K Yellepeddi -- Magnetophoresis and electret mediated transdermal delivery of drugs / Abhijeet Maurya, Cui Lili and S.Narasimha Murthy -- Microporation for enhanced transdermal drug delivery / Thakur Raghu Raj Singh, Gujral C -- Microneedle technology / Helen L. Quinn, Aaron J. Courtenay, Mary-Carmel Kearney and Ryan F. Donnelly -- Intradermal delivery of active cosmeceutical ingredients / Andrzej M. Bugaj -- Commercial and regulatory considerations in transdermal and dermal medicines development / Marc .B. Brown, Jon Lenn, Charles Evans, Sian Lim.
588 _aDescription based on print version record and CIP data provided by publisher.
520 _aThis research book covers the major aspects relating to the use of novel delivery systems in enhancing both transdermal and intradermal drug delivery. It provides a review of transdermal and intradermal drug delivery, including the history of the field and the various methods employed to produce delivery systems from different materials such as device design, construction and evaluation, so as to provide a sound background to the use of novel systems in enhanced delivery applications. Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation. Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.
650 0 _aDrug delivery systems.
650 0 _aTransdermal medication.
650 0 _aInjections, Intradermal.
650 7 _aMEDICAL / Pharmacology
_2bisacsh
650 7 _aDrug delivery systems.
_2fast
_0(OCoLC)fst00898667
650 7 _aInjections, Intradermal.
_2fast
_0(OCoLC)fst00973533
650 7 _aTransdermal medication.
_2fast
_0(OCoLC)fst01154570
650 2 _aDrug Delivery Systems.
655 4 _aElectronic books.
700 1 _aDonnelly, Ryan F.,
_eeditor.
700 1 _aSingh, Thakur Raghu Raj,
_eeditor.
776 0 8 _iPrint version:
_tNovel delivery systems for transdermal and intradermal drug delivery
_dChichester, United Kingdom : John Wiley and Sons, Inc., 2015
_z9781118734513
_w(DLC) 2015015480
830 0 _aAdvances in pharmaceutical technology.
856 4 0 _uhttp://onlinelibrary.wiley.com/book/10.1002/9781118734506
_zWiley Online Library
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