000 04062cam a2200817Ii 4500
001 ocn905991359
003 OCoLC
005 20171224114855.0
006 m o d
007 cr cnu---unuuu
008 150328s2015 gw ob 001 0 eng d
040 _aEBLCP
_beng
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019 _a910983561
020 _a9783527673049
_qelectronic bk.
020 _a3527673040
_qelectronic bk.
020 _a9783527673025
_qelectronic bk.
020 _a3527673024
_qelectronic bk.
020 _z9783527673056
_qelectronic bk.
020 _z3527673059
_qelectronic bk.
020 _a9783527673032
_qelectronic bk.
020 _a3527673032
_qelectronic bk.
020 _z9783527335824
_q(print ;
_qalk. paper)
020 _z352733582X
_q(print ;
_qalk. paper)
024 7 _a10.1002/9783527673025
_2doi
029 1 _aGBVCP
_b83642624X
029 1 _aDEBBG
_bBV043397671
035 _a(OCoLC)905991359
_z(OCoLC)910983561
050 4 _aRM301.25
_b.T44 2015eb
060 4 _aW1
_bME9613h v.65 2015
060 4 _aQV 745
072 7 _aMED
_x071000
_2bisacsh
082 0 4 _a615.19
_223
049 _aMAIN
245 0 0 _aThermodynamics and kinetics of drug binding /
_cedited by György M. Keserü and David C. Swinney.
264 1 _aWeinheim, Germany :
_bWiley-VCH Verlag GmbH & Co. KGaA,
_c[2015]
300 _a1 online resource (xxiii, 334 pages) :
_billustrations (some color)
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aMethods and principles in medicinal chemistry ;
_vvolume 65
504 _aIncludes bibliographical references and index.
520 _a"This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors."--
_cPublisher's info.
588 0 _aDescription based on print version record.
650 0 _aDrug development.
650 0 _aBinding sites (Biochemistry)
_xThermodynamics.
650 0 _aPharmacokinetics.
650 7 _aMEDICAL / Pharmacology
_2bisacsh
650 7 _aBinding sites (Biochemistry)
_xThermodynamics.
_2fast
_0(OCoLC)fst00831877
650 7 _aDrug development.
_2fast
_0(OCoLC)fst00898670
650 7 _aPharmacokinetics.
_2fast
_0(OCoLC)fst01060250
650 1 2 _aDrug Discovery.
650 1 2 _aReceptors, Drug.
650 2 2 _aLigands.
650 2 2 _aThermodynamics.
650 2 2 _aPharmacokinetics.
655 4 _aElectronic books.
655 0 _aElectronic books.
700 1 _aKeserü, G. M.,
_eeditor.
700 1 _aSwinney, David Carl,
_eeditor.
776 0 8 _iPrint version:
_tThermodynamics and kinetics of drug binding
_z9783527335824
_w(OCoLC)910103973
830 0 _aMethods and principles in medicinal chemistry ;
_vv. 65.
856 4 0 _uhttp://onlinelibrary.wiley.com/book/10.1002/9783527673025
_zWiley Online Library
938 _aEBL - Ebook Library
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938 _aRecorded Books, LLC
_bRECE
_nrbeEB00607612
938 _aYBP Library Services
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938 _aEBSCOhost
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938 _aIngram Digital eBook Collection
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