| 000 | 04827cam a2200613Ma 4500 | ||
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| 001 | ocn842412695 | ||
| 003 | OCoLC | ||
| 005 | 20171224114309.0 | ||
| 006 | m o d | ||
| 007 | cr |n||||||||a | ||
| 008 | 110329s2013 gw fo 000 0 eng d | ||
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_a9783527669417 _q(electronic bk.) |
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| 020 |
_a3527669418 _q(electronic bk.) |
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_a9781299448902 _q(MyiLibrary) |
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_a1299448909 _q(MyiLibrary) |
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_aNZ1 _b15905464 |
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| 035 | _a(OCoLC)842412695 | ||
| 037 |
_a476140 _bMIL |
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| 050 | 4 | _aRM301.4 | |
| 060 | 4 | _aQV 38 | |
| 082 | 0 | 4 |
_a615.1/9 _222 |
| 049 | _aMAIN | ||
| 245 | 0 | 0 |
_aModern biopharmaceuticals : _brecent success stories / _cedited by Jorg Knablein. |
| 260 |
_aWeinheim : _bWiley-VCH Verlag GmbH, _c2013. |
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| 300 | _a1 online resource (450 pages) | ||
| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 588 | 0 | _aPrint version record. | |
| 505 | 0 | _aRelated Titles; Title Page; Copyright; Dedication; Foreword by Andreas Busch; Foreword by Günter Stock; Preface; Quotes; List of Contributors; Part I: Modern Biopharmaceuticals: Research is the Best Medicine -- Sanitas Summum Bonus; Chapter 1: Twenty Thousand Years of Biotech -- From "Traditional" to "Modern Biotechnology"; 1.1 Biotechnology -- The Science Creating Life; 1.2 The Inauguration of Biotechnology; 1.3 From "Traditional" to "Modern Biotechnology"; 1.4 A Small Molecule from Bacteria -- A Huge Importance for Mankind; 1.5 Biopharmaceuticals -- The Mainstay of Modern Biotechnology | |
| 505 | 8 | _a1.6 Transformation of the Pharma Industry Through Biotechnology1.7 Biopharmaceutical Production -- Uncorking Bottlenecks or Wasting Surplus Capacity?; 1.8 Conclusion and Outlook; References; Part II: Modern Biopharmaceutical Development Using Stem Cells, Tissues, and Whole Animals; Chapter 2: Induced Pluripotency as Substitute of Somatic Cell Nuclear Transfer? -- The Impact of Induced Pluripotent Stem Cells on Drug Discovery and Regenerative Biopharmaceuticals; 2.1 Introduction; 2.2 Derivation and Growth of hESC; 2.3 Signaling Pathways and Transcription Factors | |
| 505 | 8 | _a2.4 Differentiation and Applications of hESC2.5 Patient-Specific Nuclear Transfer Stem Cells; 2.6 Patient-Specific Pluripotent Cells Through Direct Reprogramming of Adult Somatic Cells; 2.7 Concluding Remarks and Outlook; Acknowledgment; References; Chapter 3: Pluripotent Stem Cell-Derived Cardiomyocytes for Industrial and Clinical Applications; 3.1 Introduction; 3.2 Pluripotent Stem Cells; 3.3 High-Yield Differentiation of Pluripotent Stem Cells into Cardiomyocytes; 3.4 Purification of Pluripotent Stem Cell-Derived Cardiomyocytes; 3.5 Cardiomyocytes at an Industrial Scale | |
| 505 | 8 | _a3.6 Utilization of Tissue Engineering Technologies to Advance Cellular Maturity3.7 Concluding Remarks; References; Chapter 4: Industrialization of Functional Mouse Genomics Technologies for Biopharmaceutical Drug Discovery and Development; 4.1 Introduction; 4.2 The Mouse Genetics Story; 4.3 Establishing Inducible Gene Targeting Tools; 4.4 RNAi -- Talking About a Revolution?; 4.5 Further Shortening the Generation Timeline for RNAi Mouse Models; 4.6 Adapting the Mouse Genetics Toolbox for New Applications; References; Part III: Innovative Development Tools for Modern Biopharmaceuticals | |
| 505 | 8 | _aChapter 5: Standardized Solutions for Quantitative and Real-Time RT-PCR to Accelerate Biopharmaceutical Development5.1 Introduction; 5.2 Potential of Real-Time RT-PCR in Biopharmaceutical Development; 5.3 Accurate Gene Expression Analysis Depends on Standardized Preanalytical Steps; 5.4 Accuracy of Real-Time RT-PCR Depends on Efficient cDNA Synthesis; 5.5 Integration of Preanalytical Steps Streamlines Gene Expression Analysis; 5.6 Overview of Methods for Real-Time RT-PCR; 5.7 Developments in Real-Time PCR Instrumentation; 5.8 The Need for Better Standardization of Quantification Methods | |
| 650 | 0 | _aBiopharmaceutics. | |
| 650 | 7 |
_aBiopharmaceutics. _2fast _0(OCoLC)fst00832650 |
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| 655 | 4 | _aElectronic books. | |
| 700 | 1 | _aKnäblein, Jörg. | |
| 776 | 0 | 8 |
_iPrint version: _z9781299448902 |
| 856 | 4 | 0 |
_uhttp://onlinelibrary.wiley.com/book/10.1002/9783527669417 _zWiley Online Library |
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