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008 110806s2012 gw a ob 001 0 eng d
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019 _a768230386
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020 _a9783527640010
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020 _a3527640010
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020 _a9781283869904
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020 _z3527326987
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035 _a(OCoLC)808347872
_z(OCoLC)768230386
_z(OCoLC)796024019
_z(OCoLC)797919435
_z(OCoLC)822017643
_z(OCoLC)961568915
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037 _a10.1002/9783527639991
_bWiley InterScience
_nhttp://www3.interscience.wiley.com
050 4 _aQH447
_b.G463 2012eb
072 7 _aSCI
_x029000
_2bisacsh
082 0 4 _a572.8619
_223
049 _aMAIN
245 0 0 _aGenome organization and function in the cell nucleus /
_cedited by Karsten Rippe.
260 _aHeidelberg, Germany :
_bWiley-VCH,
_c©2012.
300 _a1 online resource (xxv, 568 pages) :
_billustrations
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _adata file
_2rda
380 _aBibliography
504 _aIncludes bibliographical references and index.
505 0 _aFront Matter -- Deciphering DNA Sequence Information / Mark Kaganovich, Michael Snyder -- DNA Methylation / Carina Frauer, Fabio Spada, Heinrich Leonhardt -- Nucleosomes as Control Elements for Accessing the Genome / Mekonnen Lemma Dechassa, Karolin Luger -- Histone Modifications and Their Role as Epigenetic Marks / Karl Nightingale -- Chromatin Remodeling and Nucleosome Positioning / Gernot L̃ngst, Vladimir B Teif, Karsten Rippe -- The Folding of the Nucleosome Chain / Karsten Rippe -- The Crowded Environment of the Genome / Ron Hancock -- The Nuclear Lamina as a Chromatin Organizer / Nikolaj Zuleger, Eric C Schirmer -- Three-Dimensional Architecture of Genomes / Job Dekker -- Transcriptional Initiation: Frequency, Bursting, and Transcription Factories / Kieran Finan, Peter R Cook -- Processing of mRNA and Quality Control / Ute Schmidt, Edouard Bertrand -- The Nucleolus / Saskia Hutten, Belinda J Westman, Fraṅois-Michel Boisvert, Silvana van Koningsbruggen, Angus I Lamond -- Non-Coding RNAs as Regulators of Transcription and Genome Organization / Katalin Fejes T̤th, Gregory Hannon -- RNA Networks as Digital Control Circuits of Nuclear Functions / John S Mattick -- DNA Replication and Inheritance of Epigenetic States / Armelle Corpet, Genevïve Almouzni -- Interplay and Quality Control of DNA Damage Repair Mechanisms / Berina Eppink, Jeroen Essers, Roland Kanaar -- Higher Order Chromatin Organization and Dynamics / Hilmar Strickfaden, Thomas Cremer, Karsten Rippe -- The Mitotic Chromosome: Structure and Mechanics / John F Marko -- Meiotic Chromosome Dynamics / Nancy Kleckner, Liangran Zhang, Beth Weiner, Denise Zickler -- Understanding Genome Function: Quantitative Modeling of Chromatin Folding and Chromatin-Associated Processes / Mariliis Tark-Dame, Martijn S Luijsterburg, Dieter W Heermann, Roel van Driel -- Index.
520 _aBy way of its clear and logical structure, as well as abundant highresolution illustrations, this is a systematic survey of the players and pathways that control genome function in the mammalian cell nucleus. As such, this handbook and reference ties together recently gainedknowledge from a variety of scientific disciplines and approaches, dissecting all major genomic events: transcription, replication, repair, recombination and chromosome segregation. A special emphasis is put on transcriptional control, including genome-wide interactions andnon-coding RNAs, chromatin structure, ep.
650 0 _aMammals
_xGenetics.
650 0 _aGenomes.
650 0 _aMolecular genetics.
650 4 _aGenomes.
650 4 _aMammals
_xGenetics.
650 4 _aMolecular genetics.
650 7 _aSCIENCE
_xLife Sciences
_xGenetics & Genomics.
_2bisacsh
650 7 _aGenomes.
_2fast
_0(OCoLC)fst00940225
650 7 _aMammals
_xGenetics.
_2fast
_0(OCoLC)fst01006983
650 7 _aMolecular genetics.
_2fast
_0(OCoLC)fst01024797
655 4 _aElectronic books.
655 7 _aElectronic books.
_2local
700 1 _aRippe, Karsten.
776 0 8 _iPrint version:
_tGenome organization and function in the cell nucleus.
_dWeinheim : Wiley-VCH ; Chichester : John Wiley [distributor], 2011
_z9783527326983
_w(OCoLC)751739775
856 4 0 _uhttp://onlinelibrary.wiley.com/book/10.1002/9783527639991
_zWiley Online Library
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