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| 001 | ocn793995928 | ||
| 003 | OCoLC | ||
| 005 | 20171224113947.0 | ||
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| 008 | 120521s2012 nju ob 001 0 eng d | ||
| 010 | _z 2011047552 | ||
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_a615.1/9 _223 |
| 049 | _aMAIN | ||
| 245 | 0 | 0 |
_aApplications of transition metal catalysis in drug discovery and development : _ban industrial perspective / _cedited by Matthew L. Crawley, Barry M. Trost. |
| 260 |
_aHoboken, N.J. : _bJohn Wiley & Sons, _c©2012. |
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| 300 | _a1 online resource (xviii, 356 pages) | ||
| 336 |
_atext _btxt _2rdacontent |
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_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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_adata file _2rda |
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| 380 | _aBibliography | ||
| 504 | _aIncludes bibliographical references and index. | ||
| 505 | 0 | _aApplications of TRANSITION METAL CATALYSIS in Drug Discovery and Development; Contents; Preface; Contributors; About the Authors; 1 Transition Metal Catalysis in the Pharmaceutical Industry; 1.1 Overview of Catalysis; 1.2 Transition Metal Catalysis in the Pharmaceutical Industry; 1.2.1 Cross-Couplings for the Formation of Carbon-Carbon Bonds; 1.2.2 Cross-Couplings for the Formation of Carbon-Heteroatom Bonds; 1.2.3 Asymmetric Hydrogenation; 1.2.4 Oxidative Catalysis; 1.2.5 Asymmetric Addition Reactions; 1.2.6 Metathesis; 1.3 Challenges in Taking Catalysis to Industrial Scales. | |
| 520 | _a"This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development."--Provided by publisher. | ||
| 588 | 0 | _aPrint version record. | |
| 650 | 0 | _aCatalysis. | |
| 650 | 0 | _aTransition metals. | |
| 650 | 0 | _aPharmacy. | |
| 650 | 1 | 2 | _aDrug Discovery. |
| 650 | 2 | 2 | _aCatalysis. |
| 650 | 2 | 2 |
_aPharmaceutical Preparations _xchemistry. |
| 650 | 2 | 2 | _aTransition Elements. |
| 650 | 4 | _aMedicine. | |
| 650 | 7 |
_aMEDICAL _xDrug Guides. _2bisacsh |
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| 650 | 7 |
_aMEDICAL _xNursing _xPharmacology. _2bisacsh |
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| 650 | 7 |
_aMEDICAL _xPharmacology. _2bisacsh |
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| 650 | 7 |
_aMEDICAL _xPharmacy. _2bisacsh |
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| 650 | 7 |
_aCatalysis. _2fast _0(OCoLC)fst00848867 |
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| 650 | 7 |
_aPharmacy. _2fast _0(OCoLC)fst01060285 |
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| 650 | 7 |
_aTransition metals. _2fast _0(OCoLC)fst01154781 |
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| 655 | 4 | _aElectronic books. | |
| 655 | 7 |
_aElectronic books. _2local |
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| 700 | 1 | _aCrawley, Matthew L. | |
| 700 | 1 | _aTrost, Barry M. | |
| 776 | 0 | 8 |
_iPrint version: _aCrawley, Matthew L. _tApplications of Transition Metal Catalysis in Drug Discovery and Development : An Industrial Perspective. _dHoboken : John Wiley & Sons, ©2012 _z9780470631324 |
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_uhttp://onlinelibrary.wiley.com/book/10.1002/9781118309872 _zWiley Online Library |
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