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Khulna University of Engineering & Technology
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Attrition in the pharmaceutical industry : reasons, implications, and pathways forward / edited by Alexander A. Alex, C. John Harris, Dennis A. Smith.

By: Alex, Alexander A [editor.].
Contributor(s): Harris, C. John [editor.] | Smith, Dennis A [editor.].
Material type: materialTypeLabelBookPublisher: Hoboken, New Jersey : John Wiley & Sons, 2015Description: 1 online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9781118914342 (epub); 1118914341 (epub); 9781118819449 (pdf); 1118819446 (pdf); 9781118819586; 1118819586; 1118679679 (cloth); 9781118679678 (cloth).Subject(s): Pharmaceutical industry -- Management | Pharmaceutical industry -- Capital productivity | Industrial efficiency | Drug development | Drug development | Industrial efficiency | Pharmaceutical industry -- Capital productivity | Pharmaceutical industry -- Management | MEDICAL / PharmacologyGenre/Form: Electronic books.Additional physical formats: Print version:: Attrition in the pharmaceutical industryDDC classification: 615.1068/5 Online resources: Wiley Online Library
Contents:
Attrition in drug discovery and development / Scott Boyer, Clive Brealey and Andrew M. Davis -- Compound attrition at the pre-clinical phase / Cornelis E.C.A. Hop -- Attrition in phase I / Dennis A. Smith and Thomas A. Baillie -- Compound attrition in phase II/III / Alexander Alex, C. John Harris, Wilma W. Keighley and Dennis A. Smith -- Post-marketing attrition / Dennis A. Smith -- Influence of the regulatory environment on attrition / Robert T. Clay -- Experimental screening strategies to reduce attrition risk / Marie-Claire Peakman, Matthew Troutman, Rose Gonzales and Anne Schmidt -- Medicinal chemistry strategies to prevent compound attrition / J. Richard Morphy -- Influence of phenotypic and target-based screening strategies on compound attrition and project choice / Andrew Bell, Wolfgang Fecke and Christine Williams -- In silico approaches to address compound attrition / Peter Gedeck, Christian Kramer, Richard Lewis -- Current and future strategies for improving drug discovery efficiency / Peter Mbugua Njogu and Kelly Chibale -- Impact of investment strategies, organizational structure and corporate environment on attrition, and future investment strategies to reduce attrition / Geoff Lawton.
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Includes index.

Attrition in drug discovery and development / Scott Boyer, Clive Brealey and Andrew M. Davis -- Compound attrition at the pre-clinical phase / Cornelis E.C.A. Hop -- Attrition in phase I / Dennis A. Smith and Thomas A. Baillie -- Compound attrition in phase II/III / Alexander Alex, C. John Harris, Wilma W. Keighley and Dennis A. Smith -- Post-marketing attrition / Dennis A. Smith -- Influence of the regulatory environment on attrition / Robert T. Clay -- Experimental screening strategies to reduce attrition risk / Marie-Claire Peakman, Matthew Troutman, Rose Gonzales and Anne Schmidt -- Medicinal chemistry strategies to prevent compound attrition / J. Richard Morphy -- Influence of phenotypic and target-based screening strategies on compound attrition and project choice / Andrew Bell, Wolfgang Fecke and Christine Williams -- In silico approaches to address compound attrition / Peter Gedeck, Christian Kramer, Richard Lewis -- Current and future strategies for improving drug discovery efficiency / Peter Mbugua Njogu and Kelly Chibale -- Impact of investment strategies, organizational structure and corporate environment on attrition, and future investment strategies to reduce attrition / Geoff Lawton.

Description based on print version record and CIP data provided by publisher.

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Khulna University of Engineering & Technology
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