Cancer as a metabolic disease : (Record no. 11933)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 06284cam a2200805Mi 4500 |
| 001 - CONTROL NUMBER | |
| control field | ocn793995949 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20171224113947.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION | |
| fixed length control field | m o d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr |n|---||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 120521s2012 nju ob 001 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | EBLCP |
| Language of cataloging | eng |
| Description conventions | pn |
| Transcribing agency | EBLCP |
| Modifying agency | OCLCQ |
| -- | CUS |
| -- | DG1 |
| -- | YDXCP |
| -- | OHI |
| -- | N$T |
| -- | TEFOD |
| -- | OCLCF |
| -- | OCLCQ |
| -- | OCLCO |
| -- | RECBK |
| -- | CNSPO |
| -- | NLGGC |
| -- | TEFOD |
| -- | OCLCQ |
| -- | COO |
| -- | OCLCQ |
| -- | DG1 |
| 019 ## - | |
| -- | 796087997 |
| -- | 864910740 |
| -- | 872697557 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781118310311 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1118310314 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781118310298 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1118310292 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781118310304 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1118310306 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 9780470584927 |
| Qualifying information | (cloth) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 0470584920 |
| Qualifying information | (cloth) |
| 028 01 - PUBLISHER NUMBER | |
| Publisher number | EB00063323 |
| Source | Recorded Books |
| 029 1# - (OCLC) | |
| OCLC library identifier | AU@ |
| System control number | 000049595558 |
| 029 1# - (OCLC) | |
| OCLC library identifier | DEBBG |
| System control number | BV041049299 |
| 029 1# - (OCLC) | |
| OCLC library identifier | NZ1 |
| System control number | 14857436 |
| 029 1# - (OCLC) | |
| OCLC library identifier | ZWZ |
| System control number | 176959769 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)793995949 |
| Canceled/invalid control number | (OCoLC)796087997 |
| -- | (OCoLC)864910740 |
| -- | (OCoLC)872697557 |
| 037 ## - SOURCE OF ACQUISITION | |
| Stock number | 9CB1EADD-C87E-47D5-8E45-0D6294D5C400 |
| Source of stock number/acquisition | OverDrive, Inc. |
| Note | http://www.overdrive.com |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC262 |
| Item number | .S49 2012 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QZ200 |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | QZ 200 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 062000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.99 |
| -- | 616.9940564 |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | MAIN |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Seyfried, Thomas N., |
| Dates associated with a name | 1946- |
| 245 10 - TITLE STATEMENT | |
| Title | Cancer as a metabolic disease : |
| Remainder of title | on the origin, management, and prevention of cancer / |
| Statement of responsibility, etc | Thomas Seyfried. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc | Hoboken : |
| Name of publisher, distributor, etc | John Wiley & Sons, |
| Date of publication, distribution, etc | 2012. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (472 pages) |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Cancer as a Metabolic Disease; Contents; Foreword; Preface; 1. Images of Cancer; How Cancer is Viewed; References; 2. Confusion Surrounds the Origin of Cancer; The Oncogenic Paradox; Hallmarks of Cancer; Reassessment; References; 3. Cancer Models; Problems with Some Cancer Models; Animal Charges as a Major Impediment to Cancer Research; Problems with Tumor Histological Classification; Personal Perspective on Cancer; References; 4. Energetics of Normal Cells and Cancer Cells; Metabolic Homeostasis; The Constancy of the D G'ATP; ATP Production in Normal Cells and Tumor Cells. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Energy Production Through Glucose Fermentation; Glutaminolysis with or without Lactate Production; Transamination Reactions; TCA Cycle, Substrate-Level Phosphorylation; Cholesterol Synthesis and Hypoxia; Summary; References; 5. Respiratory Dysfunction in Cancer Cells; Normal Mitochondria; Morphological Defects in Tumor Cell Mitochondria; Proteomic Abnormalities in Tumor Cell Mitochondria; Lipidomic Abnormalities in Tumor Cell Mitochondria; Cardiolipin: A Mitochondrial-Specific Lipid; Cardiolipin and Abnormal Energy Metabolism in Tumor Cells. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Complicating Influence of the In Vitro Growth Environment on Cardiolipin Composition and Energy Metabolism; Mitochondrial Uncoupling and Cancer; Cancer Cell Heat Production and Uncoupled Mitochondria; Personal Perspective; Summary; References; 6. The Warburg Dispute; Sidney Weinhouse's Criticisms of the Warburg Theory; Alan Aisenberg's Criticisms of the Warburg Theory; Sidney Colowick's Assessment of the Aisenberg Monograph; Apples and Oranges; References; 7. Is Respiration Normal in Cancer Cells?; Pseudo-Respiration. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | How Strong is the Scientific Evidence Showing that Tumor Cells can Produce Energy Through OxPhos?; OxPhos Origin of ATP in Cancer Cells Reevaluated; What About OxPhos Expression in Other Tumors?; The Pedersen Review on Tumor Mitochondria and the Bioenergetics of Cancer Cells; References; 8. Is Mitochondrial Glutamine Fermentation a Missing Link in the Metabolic Theory of Cancer?; Amino Acid Fermentation can Maintain Cellular Energy Homeostasis During Anoxia; Evidence Suggesting that Metastatic Mouse Cells Derive Energy from Glutamine Fermentation. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Fermentation Energy Pathways can Drive Cancer Cell Viability Under Hypoxia; Competing Explanations for the Metabolic Origin of Cancer; Chapter Summary; References; 9. Genes, Respiration, Viruses, and Cancer; Does Cancer have a Genetic Origin?; Respiratory Insufficiency as the Origin of Cancer; Germline Mutations, Damaged Respiration, and Cancer; Somatic Mutations and Cancer; Revisiting the Oncogene Theory; Mitochondrial Mutations and the Absence or Presence of Cancer; Viral Infection, Damaged Respiration, and the Origin of Cancer; Summary; References. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 10. Respiratory Insufficiency, the Retrograde Response, and the Origin of Cancer. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requiring metabolic solutions for its management and prevention. |
| 588 0# - | |
| -- | Print version record. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cancer |
| General subdivision | Prevention. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neoplasms |
| General subdivision | diet therapy. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neoplasms |
| General subdivision | metabolism. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Energy Metabolism. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Ketogenic Diet. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Mitochondria |
| General subdivision | metabolism. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Oncology. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Cancer |
| General subdivision | Prevention. |
| Source of heading or term | fast |
| -- | (OCoLC)fst00845452 |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Print version: |
| Main entry heading | Seyfried, Thomas N., 1946- |
| Title | Cancer as a Metabolic Disease : On the Origin, Management, and Prevention of Cancer. |
| Place, publisher, and date of publication | Hoboken : John Wiley & Sons, ©2012 |
| International Standard Book Number | 9780470584927 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://onlinelibrary.wiley.com/book/10.1002/9781118310311 |
| Public note | Wiley Online Library |
| 938 ## - | |
| -- | EBL - Ebook Library |
| -- | EBLB |
| -- | EBL861782 |
| 938 ## - | |
| -- | EBSCOhost |
| -- | EBSC |
| -- | 518534 |
| 938 ## - | |
| -- | Recorded Books, LLC |
| -- | RECE |
| -- | rbeEB00063323 |
| 938 ## - | |
| -- | YBP Library Services |
| -- | YANK |
| -- | 7293117 |
| 938 ## - | |
| -- | YBP Library Services |
| -- | YANK |
| -- | 7643983 |
| 938 ## - | |
| -- | YBP Library Services |
| -- | YANK |
| -- | 12671959 |
| 994 ## - | |
| -- | 92 |
| -- | DG1 |
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