Antibacterial agents : chemistry, mode of action, mechanisms of resistance, and clinical applications /
Rosaleen Anderson [and others].
- Oxford : Wiley-Blackwell, 2012.
- 1 online resource (xiv, 363 pages) : illustrations (some color)
Includes bibliographical references and index.
Introduction to microorganisms and antibacterial chemotherapy -- Agents targeting DNA -- Agents targeting metabolic processes -- Agents targeting protein synthesis -- Agents targeting cell-wall synthesis.
"Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated "lab-to-clinic" approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements."--
9781118325421 1118325427
10.1002/9781118325421 Wiley InterScience http://www3.interscience.wiley.com
Antibacterial agents.
Antibacterial agents.
Electronic books.
RM409 / .A58 2012eb
615.7922
Includes bibliographical references and index.
Introduction to microorganisms and antibacterial chemotherapy -- Agents targeting DNA -- Agents targeting metabolic processes -- Agents targeting protein synthesis -- Agents targeting cell-wall synthesis.
"Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated "lab-to-clinic" approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements."--
9781118325421 1118325427
10.1002/9781118325421 Wiley InterScience http://www3.interscience.wiley.com
Antibacterial agents.
Antibacterial agents.
Electronic books.
RM409 / .A58 2012eb
615.7922