Applications of transition metal catalysis in drug discovery and development : an industrial perspective /
edited by Matthew L. Crawley, Barry M. Trost.
- Hoboken, N.J. : John Wiley & Sons, ©2012.
- 1 online resource (xviii, 356 pages)
Includes bibliographical references and index.
Applications of TRANSITION METAL CATALYSIS in Drug Discovery and Development; Contents; Preface; Contributors; About the Authors; 1 Transition Metal Catalysis in the Pharmaceutical Industry; 1.1 Overview of Catalysis; 1.2 Transition Metal Catalysis in the Pharmaceutical Industry; 1.2.1 Cross-Couplings for the Formation of Carbon-Carbon Bonds; 1.2.2 Cross-Couplings for the Formation of Carbon-Heteroatom Bonds; 1.2.3 Asymmetric Hydrogenation; 1.2.4 Oxidative Catalysis; 1.2.5 Asymmetric Addition Reactions; 1.2.6 Metathesis; 1.3 Challenges in Taking Catalysis to Industrial Scales.
"This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development."--Provided by publisher.
9781118309872 1118309871 9781118309865 1118309863 9780470631324 0470631325 9781280592386 1280592389 9781118309834 1118309839
9786613622211
EB00063317 Recorded Books
362221 MIL
Catalysis.
Transition metals.
Pharmacy.
Drug Discovery.
Catalysis.
Pharmaceutical Preparations--chemistry.
Transition Elements.
Medicine.
MEDICAL--Drug Guides.
MEDICAL--Nursing--Pharmacology.
MEDICAL--Pharmacology.
MEDICAL--Pharmacy.
Catalysis.
Pharmacy.
Transition metals.
Electronic books.
Electronic books.
QV744
615.1/9
QV 744
Includes bibliographical references and index.
Applications of TRANSITION METAL CATALYSIS in Drug Discovery and Development; Contents; Preface; Contributors; About the Authors; 1 Transition Metal Catalysis in the Pharmaceutical Industry; 1.1 Overview of Catalysis; 1.2 Transition Metal Catalysis in the Pharmaceutical Industry; 1.2.1 Cross-Couplings for the Formation of Carbon-Carbon Bonds; 1.2.2 Cross-Couplings for the Formation of Carbon-Heteroatom Bonds; 1.2.3 Asymmetric Hydrogenation; 1.2.4 Oxidative Catalysis; 1.2.5 Asymmetric Addition Reactions; 1.2.6 Metathesis; 1.3 Challenges in Taking Catalysis to Industrial Scales.
"This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development."--Provided by publisher.
9781118309872 1118309871 9781118309865 1118309863 9780470631324 0470631325 9781280592386 1280592389 9781118309834 1118309839
9786613622211
EB00063317 Recorded Books
362221 MIL
Catalysis.
Transition metals.
Pharmacy.
Drug Discovery.
Catalysis.
Pharmaceutical Preparations--chemistry.
Transition Elements.
Medicine.
MEDICAL--Drug Guides.
MEDICAL--Nursing--Pharmacology.
MEDICAL--Pharmacology.
MEDICAL--Pharmacy.
Catalysis.
Pharmacy.
Transition metals.
Electronic books.
Electronic books.
QV744
615.1/9
QV 744