Peptide drug discovery and development : translational research in academia and industry /
edited by Miguel Castanho and Nuno C. Santos.
- Weinheim : Wiley-VCH, ©2011.
- 1 online resource (xix, 370 pages) : illustrations
Includes bibliographical references and index.
Front Matter -- The Academia-Market Bouncing of Peptide Drugs : Challenges and Strategies in Translational Research with Peptide Drugs. Peptides as Leads for Drug Discovery / Paul J Edwards, Steven R LaPlante -- Marketing Antimicrobial Peptides: A Critical Academic Point of View / Eduard Bardaj̕ -- Oral Peptide Drug Delivery: Strategies to Overcome Challenges / Josias H Hamman, Jan H Steenekamp -- Rational Design of Amphipathic a-Helical and Cyclic [beta]- Sheet Antimicrobial Peptides: Specificity and Therapeutic Potential / Wendy J Hartsock, Robert S Hodges -- Conotoxin-Based Leads in Drug Design / Muharrem Akcan, David J Craik -- Plant Antimicrobial Peptides: From Basic Structures to Applied Research / Suzana M Ribeiro, Simoni C Dias, Octavio L Franco -- Peptide Drugs' Translational Tales : Peptide Drugs before, Through and after Industry Pipelines. Omiganan Pentahydrochloride: A Novel, Broad-Spectrum Antimicrobial Peptide for Topical Use / Evelina Rubinchik, Dominique Dugourd -- Turning Endogenous Peptides into New Analgesics: The Example of Kyotorphin Derivatives / Marta M B Ribeiro, Isa D Serrano, S̤nia S̀ Santos -- The Development of Romiplostim : A Therapeutic Peptibody Used to Stimulate Platelet Production / Graham Molineux, Ping Wei -- HIV vs. HIV: Turning HIV-Derived Peptides into Drugs / Henri G Franquelim, Pedro M Matos, A Salom̌ Veiga -- Sifuvirtide, A Novel HIV-1 Fusion Inhibitor / Xiaobin Zhang, Hao Wu, Fengshan Wang -- Whither Peptide Drugs? Peptides Shaping the Future of Drug Development. Endogenous Peptides and Their Receptors as Drug Discovery Targets for the Treatment of Metabolic Disease / Mary Ann Pelleymounter, Yuren Wang, Ning Lee -- Translation of Motilin and Ghrelin Receptor Agonists into Drugs for Gastrointestinal Disorders / Gareth J Sanger, John Broad, David H Alpers -- Of Mice and Men: Translational Research on Amylin Agonism / Jonathan D Roth, Christine M Mack, James L Trevaskis, David G Parkes -- Peptides and Polypeptides as Immunomodulators and Their Consequential Therapeutic Effect in Multiple Sclerosis and Other Autoimmune Diseases / Ruth Arnon, Michael Sela, Rina Aharoni -- Development of Antibody Fragments for Therapeutic Applications / Sofia Carte-Real, Frederico Aires da Silva, Joao Gonzalves -- Index.
9783527636730 3527636730 9783527636754 3527636757
9786613302519
10.1002/9783527636730 Wiley InterScience http://www3.interscience.wiley.com
Peptide drugs.
Peptide drugs--Case studies.
Drug development.
MEDICAL--Pharmacology.
Drug development.
Peptide drugs.
Electronic books.
Case studies.
Electronic books.
RS431.P38 / P47 2011
615.3
Includes bibliographical references and index.
Front Matter -- The Academia-Market Bouncing of Peptide Drugs : Challenges and Strategies in Translational Research with Peptide Drugs. Peptides as Leads for Drug Discovery / Paul J Edwards, Steven R LaPlante -- Marketing Antimicrobial Peptides: A Critical Academic Point of View / Eduard Bardaj̕ -- Oral Peptide Drug Delivery: Strategies to Overcome Challenges / Josias H Hamman, Jan H Steenekamp -- Rational Design of Amphipathic a-Helical and Cyclic [beta]- Sheet Antimicrobial Peptides: Specificity and Therapeutic Potential / Wendy J Hartsock, Robert S Hodges -- Conotoxin-Based Leads in Drug Design / Muharrem Akcan, David J Craik -- Plant Antimicrobial Peptides: From Basic Structures to Applied Research / Suzana M Ribeiro, Simoni C Dias, Octavio L Franco -- Peptide Drugs' Translational Tales : Peptide Drugs before, Through and after Industry Pipelines. Omiganan Pentahydrochloride: A Novel, Broad-Spectrum Antimicrobial Peptide for Topical Use / Evelina Rubinchik, Dominique Dugourd -- Turning Endogenous Peptides into New Analgesics: The Example of Kyotorphin Derivatives / Marta M B Ribeiro, Isa D Serrano, S̤nia S̀ Santos -- The Development of Romiplostim : A Therapeutic Peptibody Used to Stimulate Platelet Production / Graham Molineux, Ping Wei -- HIV vs. HIV: Turning HIV-Derived Peptides into Drugs / Henri G Franquelim, Pedro M Matos, A Salom̌ Veiga -- Sifuvirtide, A Novel HIV-1 Fusion Inhibitor / Xiaobin Zhang, Hao Wu, Fengshan Wang -- Whither Peptide Drugs? Peptides Shaping the Future of Drug Development. Endogenous Peptides and Their Receptors as Drug Discovery Targets for the Treatment of Metabolic Disease / Mary Ann Pelleymounter, Yuren Wang, Ning Lee -- Translation of Motilin and Ghrelin Receptor Agonists into Drugs for Gastrointestinal Disorders / Gareth J Sanger, John Broad, David H Alpers -- Of Mice and Men: Translational Research on Amylin Agonism / Jonathan D Roth, Christine M Mack, James L Trevaskis, David G Parkes -- Peptides and Polypeptides as Immunomodulators and Their Consequential Therapeutic Effect in Multiple Sclerosis and Other Autoimmune Diseases / Ruth Arnon, Michael Sela, Rina Aharoni -- Development of Antibody Fragments for Therapeutic Applications / Sofia Carte-Real, Frederico Aires da Silva, Joao Gonzalves -- Index.
9783527636730 3527636730 9783527636754 3527636757
9786613302519
10.1002/9783527636730 Wiley InterScience http://www3.interscience.wiley.com
Peptide drugs.
Peptide drugs--Case studies.
Drug development.
MEDICAL--Pharmacology.
Drug development.
Peptide drugs.
Electronic books.
Case studies.
Electronic books.
RS431.P38 / P47 2011
615.3